Walking Function After Cervical Contusion and Distraction Spinal Cord Injuries in Rats
نویسندگان
چکیده
منابع مشابه
Olfactory glia transplantation into cervical spinal cord contusion injuries.
OBJECT The results of olfactory ensheathing cell (OEC) transplantation have raised great expectations as a potential treatment for spinal cord injury (SCI). Its capacity to promote functional neural repair, however, remains unclear. The authors studied axonal growth and locomotor recovery after C-7 contusion injury and OEC transplantation in adult rats. METHODS Twenty-four male Wistar rats un...
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Cervical injuries are the most common form of SCI. In this study, we used a neuromodulatory approach to promote skilled movement recovery and repair of the corticospinal tract (CST) after a moderately severe C4 midline contusion in adult rats. We used bilateral epidural intermittent theta burst (iTBS) electrical stimulation of motor cortex to promote CST axonal sprouting and cathodal trans-spin...
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Introduction: Spinal cord injury (SCI) is one of the most serious clinical diseases, which not only affects the patient's physical and mental status, but its effects will be spread to family and community. After severe spinal cord injury, astrocytes of the central nervous system (CNS) become reactive astrocytes, and play the main role of glial scar formation. The scar is a major obstacle to r...
متن کاملA contusion model of severe spinal cord injury in rats.
The translational potential of novel treatments should be investigated in severe spinal cord injury (SCI) contusion models. A detailed methodology is described to obtain a consistent model of severe SCI. Use of a stereotactic frame and computer controlled impactor allows for creation of reproducible injury. Hypothermia and urinary tract infection pose significant challenges in the post-operativ...
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ژورنال
عنوان ژورنال: Journal of Experimental Neuroscience
سال: 2019
ISSN: 1179-0695,1179-0695
DOI: 10.1177/1179069519869615